Newswise — WASHINGTON, Dec. 9, 2025 — The December issue of the Journal of Cardiac Failure (JCF), now available, offers a robust lineup of original research, expert consensus, and clinical insights that explore heart failure (HF) through a multidisciplinary, inclusive, and globally engaged lens. This issue highlights how innovation, digital health, and region-specific perspectives can reshape patient care across the spectrum of heart failure.
The December issue spotlights three pieces that exemplify the journal’s commitment to advancing science and improving outcomes:
With heart transplantation from hepatitis C–positive (HCV NAT–positive) donors increasing, clinicians face wide variation in how best to manage these recipients—ranging from prophylactic antiviral therapy to treatment only after viremia appears. This article examines current approaches, revealing significant practice heterogeneity and underscoring the need for registries and randomized trials to establish consistent, evidence-based strategies.
A study examining digital support for heart failure treatment management, this article reviews the design and goals of the AIM-POWER trial, which evaluates the digital platform BiovitalsHF. The trial aims to determine whether digital tools can improve the use, titration, and optimization of guideline-directed medical therapy (GDMT) among individuals with HFrEF—an area of growing importance as healthcare systems increasingly adopt remote management solutions.
Despite strong evidence supporting early and rapid initiation of the four pillars of GDMT in HFrEF, underuse remains pervasive in clinical practice. This article presents an Indian expert consensus, developed using the modified Delphi technique, offering practical, patient-profile-based guidance to help clinicians tailor and optimize GDMT. The consensus aims to improve real-world implementation and, ultimately, clinical outcomes for patients with HFrEF.
“The December issue reflects the spirit of what makes JCF so vital—scientific rigor paired with multidisciplinary, global perspectives that directly influence patient care,” said JCF co-editors-in-chief Robert J. Mentz, MD and Anuradha Lala, MD “These featured articles illustrate how innovation is happening on many fronts: in transplant medicine, digital therapeutics, and consensus-building across diverse clinical settings. We encourage readers to explore the full issue, which provides valuable insights for clinicians, researchers, and healthcare teams working across the heart failure community.”
View the full issue online. For interviews with authors, please contact Laura Poko at lpoko@hfsa.org.
About the Journal of Cardiac Failure
The Journal of Cardiac Failure (JCF) publishes the highest quality science in the field of heart failure with a focus on diversity, equity, and inclusion, mentorship, multidisciplinary partnerships, and patient-centeredness. Published papers span original investigator-initiated work to state-of-the-art reviews, guidelines and scientific statements, expert perspectives, early career and trainee spotlight pieces, patient and patient-partner narratives. JCF also emphasizes the power of language and prioritizes innovative approaches to dissemination of published work to reach and impact the broader heart failure community.
About the Heart Failure Society of America
The Heart Failure Society of America, Inc. (HFSA) represents the first organized effort by heart failure experts from the Americas to provide a forum for all those interested in heart function, heart failure, and congestive heart failure (CHF) research and patient care. The mission of HFSA is to provide a platform to improve and expand heart failure care through collaboration, education, innovation, research, and advocacy. HFSA members include physicians, scientists, nurses, nurse practitioners, pharmacists, trainees, other healthcare workers, and patients. For more information, visit hfsa.org.
Media Contact: Laura Poko, 301-798-4493, ext. 226, lpoko@hfsa.org
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